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HPLC-electrospray tandem mass spectrometry for simultaneous quantitation of eight plasma aminothiols: application to studies of diabetic nephropathy

Investigational (phase 3) REDEFINE dataset with an FDA filing under review

The concentration of L-serine in cerebrospinal fluid (CSF) decreases with age from a mean of 59 mol/L at the age of 1 week to a mean of 31 mol/L at the age of 10 years, suggesting that the demand for L-serine varies with age (van der Crabben et al., 2013)

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